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National Institute for Parasitic Diseases, China CDC
Jiangsu Institute of Schistosomiasis, PR China
Research Institute of Tropical Medicine , Philippines

 

 
 
 
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Identification of New Drug Leads

Time:2009-10-9

Identification of New Drug Leads for the Control of Schistosomiasis

 

David L. Williams
Immunology/Microbiology

Rush University Medical Center

Department of Biological Sciences

Illinois State University

 

            Schistosomiasis (Bilharzia or snail fever) infects 207,000,000 people in the world.  There are an estimated 280,000 deaths/year. It is a major cause of underreported morbidity. It is endemic in 75 countries and almost 800 million people are at risk. Chemotherapy is an important component of schistosomiasis control.  Praziquantel is single widely used drug. Tens of millions of people are  treated annually however rapid reinfection occurs after treatment. Resistance possible and there is still a question of resistance at present. There is an urgent need for new antischistosomal drugs.

 

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